https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9256 Wed 11 Apr 2018 09:30:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10610 Sat 24 Mar 2018 08:13:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26825 in silico screening of novel transcription inhibitors. Here, we describe our approach for the design and testing of small molecule transcription inhibitors that work by preventing the interaction between the essential transcription initiation factor σ and RNAP. With the appropriate structural information this approach can be easily modified to other essential protein-protein interactions.]]> Sat 24 Mar 2018 07:36:25 AEDT ]]>